Built during the post-war period, the Prado de San Sebastián Bus Station was the first bus station in Andalusia. It is a rationalist-style construction begun during the 1930s by the architect Rodrigo Medina Benjumea, who was commissioned to design a functional building consisting of housing and a station on the ground floor. Its sober style with simple lines and hardly any decorative elements contrasted with the regionalist trend prevailing in the constructions of the time, such as those that had been inaugurated shortly before for the Universal Exhibition of 1929.

The station appears in the film ‘Cabeza de perro’ by Santi Amodeo.